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Table 2 A list of circRNAs encoded in human cancers

From: Translation and functional roles of circular RNAs in human cancer

Gene names Cancer type Encoded protein name Cancer phenotype Refs
circSHPRH Glioma SHPRH-146aa The overexpression of SHPRH-146aa glioblastoma cells reduces their malignant behavior and tumorigenicity in vitro and in vivo [96]
circLINC-PINT Gliobalstoma PINT87aa It can suppress glioblastoma cell proliferation in vitro and in vivo [98]
circβ-catenin hepatocellular carcinoma β-catenin-370aa Silencing of circβ-catenin significantly suppresses malignant phenotypes in vitro and in vivo [102]
circFBXW7 Glioma
Breast cancer
FBXW7-185aa Knockdown of FBXW7-185aa promoted malignant phenotypes in vitro and in vivo [97]
[103]
circAKT3 Glioblastoma AKT3-174aa Knockdown of circ-AKT3 enhanced the malignant phenotypes of astrocytoma cells [101]
circPPP1R12A Colon cancer circPPP1R12A-73aa circPPP1R12A played a critical role in proliferation, migration and invasion of colon cancer cells [100]