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Fig. 3 | Molecular Cancer

Fig. 3

From: Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2

Fig. 3

The effect of SOX2OT on BCSC migration, invasion and EMT. a and b: Changes in the migratory abilities of BCSCs were determined using wound-healing assays. c and d: Changes in the invasive abilities of BCSCs were determined using transwell assays. e and f: The expression of EMT markers was determined using RT-qPCR and western blotting. g and h: The expression of EMT markers was determined using immunofluorescence. Knockdown of SOX2OT increased the expression of E-cadherin and decreased the expression of N-cadherin/vimentin in BCSCs. The data are shown as the mean ± SD. *p < 0.05; **p < 0.01

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