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Fig. 7 | Molecular Cancer

Fig. 7

From: Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2

Fig. 7

The effect of SOX2OT on bladder cancer pulmonary metastasis and the schematic diagram of the oncogenic role of SOX2OT. a and b The luciferase signals in the sh-SOX2OT group were remarkably lower than those in the sh-NC group. c There was no significant difference between the mouse weight of two treatment group. d and e The number and size of pulmonary metastases in the sh-SOX2OT group were significantly reduced compared with those in the sh-NC group. f and h Knockdown of SOX2OT decreased SOX2 expression in pulmonary metastases. g The expression of E-cadherin in the sh-SOX2OT group was remarkably higher than that in the sh-NC group. Knockdown of SOX2OT decreased N-cadherin expression in pulmonary metastases. i Schematic diagram of the oncogenic role of SOX2OT in bladder cancer

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Molecular Cancer

ISSN: 1476-4598