Fig. 1From: Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapySummary of biomarkers of the response to anti-PD-1/PD-L1 immunotherapy. The efficacy of PD-1/PD-L1 blockade therapy is mainly predicted by PD-1/PD-L1 expression, microsatellite instability, tumor mutation load, and bone marrow-derived suppressor cells. The roles and significance of POLE, TGF-β, TGF-β, NLR, ANC, IDO1, and various chemokines are summarized. Biomarkers are shown in redBack to article page