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Fig. 1 | Molecular Cancer

Fig. 1

From: Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapy

Fig. 1

Summary of biomarkers of the response to anti-PD-1/PD-L1 immunotherapy. The efficacy of PD-1/PD-L1 blockade therapy is mainly predicted by PD-1/PD-L1 expression, microsatellite instability, tumor mutation load, and bone marrow-derived suppressor cells. The roles and significance of POLE, TGF-β, TGF-β, NLR, ANC, IDO1, and various chemokines are summarized. Biomarkers are shown in red

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