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Fig. 6 | Molecular Cancer

Fig. 6

From: RETRACTED ARTICLE: Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation

Fig. 6

lncRNA AFAP1-AS1 regulates HER-2 protein level in breast cancer cells. a Immunofluorescence analysis of HER-2 protein in trastuzumab resistant cells and parental cells. b Western blot assay was performed to identify the effects of AFAP1-AS1 knockdown on HER-2 protein levels. c qRT-PCR showed that knockdown of AFAP1-AS1 had no influence on ERBB2 expression. d Overexpression of AFAP1-AS1 increased HER-2 protein level in SKBR-3 and BT474 cells. e Enhanced expression of AFAP1-AS1 showed no influence on ERBB2 expression

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