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Fig. 1 | Molecular Cancer

Fig. 1

From: mRNA vaccine: a potential therapeutic strategy

Fig. 1

Antigen-encoding mRNA expression by alphaviral replicon RNA. a DNA plasmid–based saRNA uses plasmid DNA as a carrier to transfer replicase genes and the transgene into the nucleus where the mRNA is translated. b the virus-like particle packages saRNA and delivers replicon RNA to the cytosol by the receptor-mediated endocytosis, forming an endosome. c in vitro transcribed saRNAs are delivered in saline or synthetic formulations. Created with BioRender.com

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Molecular Cancer

ISSN: 1476-4598