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Table 2 Univariate and multivariate Cox regression analyses of dfifferent parameters on overall survival

From: Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis

Parameter

Univariate Analysis

Multivariate Analysis

HR (95%CI)

P Value

HR (95%CI)

P Value

Age (≥ 60 vs. <  60 yr)

1.049 (1.020-1.078)

<0.001

1.041 (1.013-1.071)

0.004

Gender (Female vs. male)

1.692 (0.734-3.898)

0.217

–

–

TNM stage (II-III vs. I)

2.398 (1.477-3.894)

<0.001

1.405 (0.810-2.438)

0.226

Fuhrman (3+ 4 vs. 1+ 2)

2.074 (1.242-3.463)

0.005

1.689 (0.958-2.976)

0.070

Surgery type (Open vs. laparoscopy)

0.525 (0.251-1.100)

0.088

–

–

circSDHC expression (High vs. low)

3.324 (1.777-6.217)

<0.001

2.916 (1.508-5.637)

0.002

HR=hazard ratio. CI= confidence interval

    
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Molecular Cancer

ISSN: 1476-4598