Table 1 Clinicopathological characteristics of the patients enrolled in this study
From: Non-invasive lung cancer diagnosis and prognosis based on multi-analyte liquid biopsy
LC (N = 128) | BLN (N = 94) | p-value | ||||
|---|---|---|---|---|---|---|
Number | Percentage | Number | Percentage | |||
Gender | Female | 53 | 41% | 48 | 51% | 0.15 (chi-squared test) |
Male | 75 | 59% | 46 | 49% | ||
Age | Median ± SD (Range) | 63.00 ± 11.58 (30–86) | 55.00 ± 10.49 (18–79) | 1.00E-05 (Student’s t-test) | ||
Nodule Size (cm) | Median ± SD (Range) | 2.00 ± 1.35 (0.20–6.50) | 1.25 ± 1.14 (0.35–5.75) | 1.22E-03 (Student’s t-test) | ||
Histology | LUAD | 97 | 76% | |||
LUSC | 23 | 18% | ||||
LCC | 3 | 2% | ||||
SCLC | 5 | 4% | ||||
Inflammatory Lesion | 31 | 33% | ||||
Granulomatous Inflammation | 12 | 13% | ||||
Atypical Adenomatous Hyperplasia | 10 | 11% | ||||
Atypical Hyperplasia | 10 | 11% | ||||
Others | 31 | 33% | ||||
Stage | 0 | 2 | 2% | |||
IA | 54 | 42% | ||||
IB | 29 | 23% | ||||
II | 17 | 13% | ||||
III | 19 | 15% | ||||
IV | 7 | 5% | ||||
Smoking History | Current-Smoker | 29 | 23% | 15 | 16% | 0.02 (chi-squared test) |
Ex-Smoker | 21 | 16% | 8 | 9% | ||
Non-smokers | 77 | 60% | 70 | 74% | ||
Unknown | 1 | 1% | 1 | 1% | ||
Smoking Levels (pack-years) | Median ± SD (Range) | 37.50 ± 27.96 (2–120) | 20.00 ± 15.02 (5–60) | 0.01 (Student’s t-test) | ||