DDX3X: structure, physiologic functions and cancer

Table 1 DDX3X and its binding proteins

Interaction protein	Interaction region	Function	Ref
ALKBH5	211–404	Modulating m⁶A RNA Demethylation	[43]
CK1ε	456–662	Involving in WNT/β-catenin signaling	[44]
CRM1	260–517	Promoting Rev./REE-CRM1-dependent export of HIV transcripts	[39]
eIF4E	38–44	Involving in translation initiation	[18]
GSK3-β	100–662	Forming anti-apoptosis complex	[45]
PABP1	227–534	Involving in stress granules assembly	[46]
TAP/NXF1	536–662	Transported by TAP with mRNPs	[16]

ISSN: 1476-4598