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Table 1 RNA based therapeutics in clinical trials in lung cancer

From: RNA-based therapies: A cog in the wheel of lung cancer defense

Drug combination

Affected Pathway

References

Custirsen + gemcitabine + cisplatin

Clusterin

[288]

Aprinocarsen + gemcitabine + cisplatin

PKC-a

[300, 303, 304]

Imetelstat + bevacizumab

Telomerase

[286]

LY2181308 + docetaxel

Survivin

[305]

Oblimersen + paclitaxel

Bcl2

[283]

Oblimersen + carboplatin + etoposide

Bcl2

[285]