Table 1 RNA based therapeutics in clinical trials in lung cancer
From: RNA-based therapies: A cog in the wheel of lung cancer defense
| Drug combination | Affected Pathway | References |
|---|---|---|
| Custirsen + gemcitabine + cisplatin | Clusterin | [288] |
| Aprinocarsen + gemcitabine + cisplatin | PKC-a | [300, 303, 304] |
| Imetelstat + bevacizumab | Telomerase | [286] |
| LY2181308 + docetaxel | Survivin | [305] |
| Oblimersen + paclitaxel | Bcl2 | [283] |
| Oblimersen + carboplatin + etoposide | Bcl2 | [285] |