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Fig. 4 | Molecular Cancer

Fig. 4

From: FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2

Fig. 4

Upregulation of YTHDF2 is negatively associated with FBW7 expression and predicts unfavorable prognosis. a Expression of YTHDF2 in cancerous and non-cancerous ovarian tissues detected by RT-qPCR. b-c IHC staining of human the ovarian cancer tissue arrays shows that YTHDF2 expression is negatively correlated with FBW7 expression. d Expression of YTHDF2 by IHC staining of the human ovarian cancer tissue arrays. Scale bar, 200 μm. e YTHDF2 upregulation is significantly associated with better overall survival in ovarian cancer patients. f No significant correlation is observed between YTHDF2 expression and progression-free survival. * P < 0.05

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Molecular Cancer

ISSN: 1476-4598