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Table 2 Suitability of the different families of nanovectors for the vectorization of anti-cancer therapeutics

From: Delivery of cancer therapies by synthetic and bio-inspired nanovectors

Nanovector family

Chemotherapy

Radiotherapy

Gene therapy

RNA interference

TME modification

Immunotherapy

Nanoparticles

+++

++

+

+

+

+

Extracellular vesicles

+

-

+

++

NT

+

Bacterial minicells

++

NT

NT*

++

NT

NT

Virus-like particles

+

NT

+++

++

NT

+

Oncolytic viruses

-

+

+++

++

+++

+++

  1. +++: optimal; ++: adapted; +: feasible; -: not adapted.
  2. NT: never tested, TME: tumor microenvironment.
  3. * expected to be similar to RNA interference