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Fig. 6 | Molecular Cancer

Fig. 6

From: GM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma

Fig. 6

Correlations among p-JAK2, p-STAT5, and PD-L1 expression in ENKTL and PTCL tissues. a The representative immunohistochemical stainings of p-JAK2, p-STAT5, and PD-L1 in ENKTL tissues were shown. b Percent distribution of GM-CSF treatments for mature T-cell lymphoma. c Linear regression analysis of p-JAK2 and p-STAT5 immunohistochemical scores in ENKTL tissue microarray; P = 0.009, r = 0.416. d Linear regression analysis of p-STAT5 and PD-L1 immunohistochemical scores in ENKTL tissue microarray; P = 0.037, r = 0.398. e Immunohistochemical scores of p-JAK2 in patients with short-term progression after GM-CSF treatment or not. f Kaplan-Meier plots for progression-free survival analysis by the optimal cutoff value of p-JAK2 immunohistochemical scores. Samples were grouped as p-STAT5 high (H-score > 4.5), p-STAT5 low (H-score < 4.5). g Kaplan-Meier plots for overall survival analysis by the optimal cutoff value of PD-L1 immunohistochemical scores. Samples were grouped as PD-L1 high (H-score > 5.0), PD-L1 low (H-score < 5.0)

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