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Fig. 4 | Molecular Cancer

Fig. 4

From: The roles of tumor-derived exosomes in altered differentiation, maturation and function of dendritic cells

Fig. 4

Combining targeted tumor exosome inhibition or removal with exiting chemo- and immunotherapies. Tumor exosomes induce resistance to chemotherapies and counteract beneficial effects of immunotherapies including monoclonal antibodies (mAbs), adoptive transfer of NK-92 cells and possibly TDE-loaded DCs. Adjunctive inhibition or removal of TDEs may add to the therapeutic benefits of currently available chemo- and immunotherapies and could improve tumor regression

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Molecular Cancer

ISSN: 1476-4598