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Fig. 1 | Molecular Cancer

Fig. 1

From: A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2–10 ng/mL at initial biopsy

Fig. 1

Differentially expressed urine extracellular vesicle circRNAs between individuals with benign prostatic hyperplasia and those with high-grade prostate cancer using RNA sequencing. (A) In the clustered heatmap, each column represents an individual sample, and each row represents an individual circRNA. The expression values were log2 transformed. (B) Eighteen candidate circRNAs displaying higher levels in patients with high-grade prostate cancer than those with benign prostatic hyperplasia according to the criteria using |fold changes|≥ 2.0 with p values < 0.05. circRNAs = circular RNAs

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