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Fig. 8 | Molecular Cancer

Fig. 8

From: Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis

Fig. 8

Overexpression of circEYA3 is associated with poor prognosis in PDAC patients. A and B. Representative FISH images of circEYA3 expression in PDAC tissues and adjacent normal tissues, as well as in tissues from tumors with different TNM stages. Nuclei were stained with DAPI. Left panel, scale bar, 100 μm; right panel, scale bar 20 μm. C. CircEYA3 FISH scores in tissues from tumors with different TNM stages. D. Kaplan-Meier survival analysis of circEYA3 expression in PDAC patients based on our data (n = 209, P = 0.004, log-rank test). E. Schematic illustration of the circEYA3/miR-1294/c-Myc axis in PDAC cells. * P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598