Fig. 2
From: Circular RNAs’ cap-independent translation protein and its roles in carcinomas
CircRNAs translation mechanism. A The non-classical eIF4G protein (eIF4G2) directly recognizes the IRES on CircRNAs to assemble the eIF4 complex to translate the downstream ORF. B YTHDF3 can recognize m6A in CircRNAs and recruit eIF4G2 to m6A to initiate translation. C CircRNA containing infinite open reading frame (iORF) undergoes rolling circle amplification to achieve translation