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Fig. 5 | Molecular Cancer

Fig. 5

From: METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer

Fig. 5

METTL3 knockdown enhances antitumor immunity and immune infiltration. a Bioluminescent images of intraperitoneal xenografted tumors from the indicated groups for Day 12 and Day 24. b The CD3+, CD4+ and CD8+ densities and PD-L1 expression were determined by Immunohistochemical analysis in the intraperitoneal xenografted tumors. Scale bar, 20 μm. c Images of subcutaneous tumors from the indicated groups (scale bar: 1 cm). d The CD3+, CD4+ and CD8+ densities and PD-L1 expression were determined by Immunohistochemical assay in the subcutaneous xenograft models. Scale bar, 20 μm

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