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Table 3 Univariate and Multivariate Analyses of Factors Associated with Cumulative Recurrence

From: Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

Factors

Cumulative Recurrence

Multivariate

Univariate p

HR

95%CI

P value

Sex (Female vs. Male)

0.617

  

NA

Age (years) (≤60 vs. >  60)

0.987

  

NA

Smoking status (Smokers vs. Nonsmokers)

0.669

  

NA

Histological type (SCC vs. Adenocarcinomas)

0.535

  

NA

Lymph node metastasis (Yes vs. No)

0.001

0.394

0.225–0.689

0.043

Differentiation (Well and moderate vs. Poor)

0.012

  

NS

Tumor size (diameter, cm) (>  3 vs. ≤3)

0.103

  

NA

TNM (III-IV vs. I-II)

0.098

  

NS

CircUSP7 expression (High vs. Low)

0.006

2.537

1.300–4.949

0.051

  1. NA Not adopted, NS Not significantly, SCC Squamous cell carcinoma, 95%CI 95% confidence interval, HR hazard ratio; Cox proportional hazards regression model