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Table 3 Univariate and multivariate Cox regression analyses of different parameters on progression-free survival

From: circCHST15 is a novel prognostic biomarker that promotes clear cell renal cell carcinoma cell proliferation and metastasis through the miR-125a-5p/EIF4EBP1 axis

parameter

Univariate Analysis

Multivariate Analysis

HR(95%CI)

P Value

HR(95%CI)

P Value

Age(≥60 yr vs. < 60 yr)

2.381(1.198–4.733)

0.013

2.028(0.985–4.174)

0.055

Sex(male vs. female)

1.997(0.866–4.606)

0.105

2.276(0.966–5.367)

0.060

Stage(III/IV vs. I/II)

4.617(2.309–9.234)

< 0.001

2.480(1.123–5.477)

0.025

Grade(3/4 vs.1/2)

4.201(2.102–8.397)

< 0.001

2.899(1.323–6.351)

0.008

circCHST15 expression level (High vs. Low)

2.282(1.106–4.707)

0.026

2.619(1.244–5.512)

0.011

  1. HR hazard radio, CI confidence interval