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Fig. 6 | Molecular Cancer

Fig. 6

From: CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis

Fig. 6

Roles of IGF1R in vitro. A mRNA expression of IGF1R in cells post cotransfection with IGF1R siRNA and the miR-339-3p inhibitor (normalized to inh-NC + si-NC). B-F CCK-8 (B), EdU incorporation (scale bar = 100 μm) (C), flow cytometry (D), Transwell migration (normalized to inh-NC + si-NC, scale bar = 100 μm) (E) and Transwell invasion (normalized to inh-NC + si-NC, scale bar = 100 μm) (F) assays measuring the migration, proliferation, apoptosis and invasion of cells post cotransfection with IGF1R siRNA and the miR-339-3p inhibitor. The data are presented as the mean ± SD of three independent experiments. **P < 0.01, ***P < 0.001

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