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Fig. 6 | Molecular Cancer

Fig. 6

From: A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression

Fig. 6

The inhibitory effect of circAXIN1 siRNA is rescued by linear AXIN1-295aa. a Cell proliferation of AGS and N87 is inhibited by circAXIN1 siRNA and reversed by linear AXIN1-295aa transfection. b Cell migration of AGS (treated with 10 μg/mL mitomycin for 1 h) and invasion of AGS and N87 are both inhibited by circAXIN1 siRNA and rescued with linear AXIN1-295aa transfection. c The inhibitory effect of circAXIN1 siRNA on cell migration is reversed by linear AXIN1-295aa. AGS cells are treated with 10 μg/mL mitomycin for 1 h in the wound healing assay, 48 h after transfection. d Colony formation ability is suppressed in AGS cells by circAXIN1 siRNA and rescued by linear AXIN1-295aa transfection

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