Fig. 2
From: Cancer associated-fibroblast-derived exosomes in cancer progression
The communication ways between CAFs and other cells. Examples are depicted of the different manners of cross-talk between CAFs and other cell types; they can be mainly divided into three groups: (i) cell-to-cell junctions, (ii) ECM interactions and (iii) the interactions mediated by secreted cytokines, growth factors, chemokines, peptides, amino acids and EVs, including exosomes