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Fig. 2 | Molecular Cancer

Fig. 2

From: On-treatment blood TMB as predictors for camrelizumab plus chemotherapy in advanced lung squamous cell carcinoma: biomarker analysis of a phase III trial

Fig. 2

On-treatment bTMB is predictive of immunotherapy plus chemotherapy benefit. (A) Forrest plot of hazard ratio (HR) and 95% confidence interval (CI) of PFS by using different on-treatment bTMB level as the cutoff. (B) Patients with CR/PR had a significantly lower on-treatment bTMB than those with SD/PD in camrelizumab plus chemotherapy group. (C) ORR was significantly higher in patients with low on-treatment bTMB than those with high on-treatment bTMB in camrelizumab plus chemotherapy group. Lower on-treatment bTMB was associated with significantly longer PFS (D) and OS (E) than those with higher on-treatment bTMB. &, P > 0.05; *, P < 0.05; **, P < 0.01

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