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Table 1 Correlations Between circRTN4 and Clinicopathologic Features in PDAC

From: CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein

Clinicopathological Characteristics

Downregulated circRTN4 level

Unchanged circRTN4

Upregulated circRTN4

P-value

Gender

 Female

12 (34%)

6 (17%)

17 (49%)

0.0085

 Male

4 (7%)

13 (25%)

36 (68%)

 

Age, years

  < 60

6 (24%)

9 (36%)

10 (40%)

0.044

  ≥ 60

10 (16%)

10 (16%)

43 (68%)

 

Tumor size, cm

  ≤ 4

6 (12%)

14 (27%)

32 (61%)

0.095

  > 4

10 (28%)

5 (14%)

21 (58%)

 

Histological grade

 Poorly differentiated

2 (50%)

1 (25%)

1 (25%)

0.053

 Moderately differentiated

8 (12%)

15 (22%)

44 (66%)

 

 Well differentiated

4 (40%)

1 (10%)

5 (50%)

 

Tumor stage

 I-II

13 (18%)

18 (25%)

42 (57%)

0.393

 III-IV

3 (21%)

1 (7%)

10 (72%)

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