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Table 1 Clinical applications of partial ROS-related ncRNAs in cancer patients

From: The crosstalk between reactive oxygen species and noncoding RNAs: from cancer code to drug role

NcRNA

Type

Cancer

Application

Status

Identifier

MiR-373

NA

Breast cancer

Cancer diagnosis

Recruiting

NCT04720508

MiR-155

NA

Bladder cancer

Cancer diagnosis

Completed

NCT03591367

MiR-371

NA

Germ cell cancer

Cancer diagnosis

Recruiting

NCT04435756

HOTAIR

NA

Thyroid cancer

Cancer diagnosis

Unknown

NCT03469544

MiR-16

Mimic

Pleural mesothelioma lung cancer

Cancer therapy

Phase I

NCT02369198

MiR-122

ASO

Liver cancer

Cancer therapy

Phase I/II

NCT01646489, NCT01727934, NCT01872936, NCT01200420

MiR-155

ASO

T-cell lymphoma

Cancer therapy

Phase II

NCT03713320, NCT03713320

MiR-34a

Mimic

Melanoma

Cancer therapy

Phase I

NCT01829971,

NCT02862145

MtlncRNA

ASO

Unresectable tumors

Cancer therapy

Phase I

NCT02508441,

NCT03985072