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Fig. 2 | Molecular Cancer

Fig. 2

From: A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study

Fig. 2

Identification of cancer-enriched sesncRNAs in salivary exosomes of ESCC patients. A The heatmap showing the top five differently expressed small RNAs by small RNA-seq of salivary exosomes. B Confirmation of the differentially expressed salivary RNAs. C Effect of sesncRNAs on cell migration and invasion. All experiments were performed in biological triplicate. D-E The box and scatter plots of tRNA-GlyGCC-5 (left) and sRESE (right) in the CHSUMC cohort (D) and the ATH cohort (E). F The results of ROC analysis of sesncRNAs in the CHSUMC cohort. SEM (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 by unpaired t-test)

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Molecular Cancer

ISSN: 1476-4598