Table 1 Patient demographics and clinicopathological characteristics of the training and validation cohorts
| Â | CHSUMC cohort | P value | ATH cohort | P value | P value | ||
|---|---|---|---|---|---|---|---|
Variables | Healthy | Patient | Healthy | Patient | |||
(n = 120) | (n = 200) | (n = 60) | (n = 140) | ||||
| Â | n (%) | n (%) | n (%) | n (%) | |||
Age (years) | 60.69 ± 8.66 | 61.06 ± 9.05 | 0.720B | 61.13 ± 9.20 | 61.24 ± 8.65 | 0.936B | 0.852B |
Gender | |||||||
 Female | 50 (41.7) | 74 (37.0) | 0.410A | 25 (41.7) | 47 (33.6) | 0.335A | 0.566A |
 Male | 70 (58.3) | 126 (63.0) |  | 35 (58.3) | 93 (66.4) |  |  |
Tumor depthC | |||||||
 T1/T2 | NA | 58 (29.0) |  | NA | 52 (37.1) |  | 0.126A |
 T3/T4 | NA | 142 (71.0) |  | NA | 88 (62.9) |  |  |
Lymph node metastasis | |||||||
 Negative | NA | 85 (42.5) |  | NA | 70 (50.0) |  | 0.185A |
 Positive | NA | 115 (57.5) |  | NA | 70 (50.0) |  |  |
Histological differentiation | |||||||
 Poor | NA | 41 (20.5) |  | NA | 18 (12.9) |  | 0.179A |
 Moderate | NA | 99 (49.5) |  | NA | 78 (55.7) |  |  |
 Well | NA | 60 (30.0) |  | NA | 44 (31.4) |  |  |
Largest tumor dimension (cm) | NA | 4.86 ± 1.45 |  | NA | 5.01 ± 1.44 |  | 0.319B |
TNM Stage | |||||||
 I/II | NA | 78 (39.0) |  | NA | 66 (47.1) |  | 0.148A |
 III/IV | NA | 122 (61.0) |  | NA | 74 (52.9) |  |  |