Fig. 1From: The double agents in liquid biopsy: promoter and informant biomarkers of early metastases in breast cancerEmergence of Circulating Tumor Cells in Early Stage Breast Cancer. Tumor cells enter the blood stream as single CTC or cluster of CTCs endowed with attributes of immune evasion, stemness and proliferation potentials. These cells also secrete cell-free nucleic acids that may be utilized as blood-based biomarkers for detecting the presence of breast cancerBack to article page