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Fig. 5 | Molecular Cancer

Fig. 5

From: BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion

Fig. 5

Cytokines secreted from Tregs in BCL-2-positive and -negative CD4+T cells in patients with CLL (n = 45). (a), (c), and (e) Representative examples of IL-10, TGF-β, and IL-35 in BCL-2+ and BCL-2− Tregs. (b), (d), and (f) Percentage positive and MFI of IL-10, TGF-β, and IL-35 among Tregs between BCL-2-positive and -negative T cells. Differences are shown in scatter plots (*p < 0.05; ns, not significant)

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Molecular Cancer

ISSN: 1476-4598