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Fig. 7 | Molecular Cancer

Fig. 7

From: BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion

Fig. 7

Differentiation of BCL-2-positive and -negative T cells in CLL (n = 70). (a) Representative examples of naïve T cells, effector T cells (Teff), effector memory T cells (Tem), and central memory T cells (Tcm) in CD4+ and CD8+ T cells in patients with CLL. (b) Sunburst diagram for differentiation of CD4+ and CD8+ T cells. (c) and (d) Percentage of cells positive for CD4+ and CD8+ T cells between BCL-2-positive and -negative T cells. Differences are shown in scatter plots (**p < 0.01, ****p < 0.0001, ns, not significant)

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