Table 1 Clinical and biological characteristics of the 266 patients with CLL
characteristics | N = 266 | |
|---|---|---|
Male, n (%) | Â | 167(62.8) |
Median age (range), years |  | 61(30–89) |
Binet stage, n (%) | Stage A | 69(25.9) |
| Â | Stage B/C | 197(74.1) |
Presence of B-symptoms, n (%) | Â | 51(19.2) |
MBC > 5 × 109/L, n (%) |  | 210(78.9) |
Platelets < 100 × 109/L, n (%) |  | 84(31.6) |
Hemoglobin < 100 g/L, n (%) |  | 58(21.8) |
CD4/CD8 | < 1, n (%) | 52(19.5) |
|  | > 2.5, n (%) | 34(12.8) |
β2-MG > 3.5 mg/L, n (%) | 113(42.5) | |
Unmutated IGHV, n (%) | Â | 116(43.6) |
Del(17p) or TP53 mutation, n (%) | 39(14.7) | |
Del(13q), n (%) | Â | 89(33.5) |
Del(11q), n (%) | 36(13.5) | |
Risk stratification, n (%) | low | 68(25.6) |
| Â | medium | 80(30) |
| Â | high | 85(32) |
| Â | very high | 33(12.4) |