Table 2 Clinical and biological characteristics of the patients with CLL whose samples were used for single-cell sequencing
Patients | CLL | CLL1 | CLL2 | CLL4 | CLL5 | CLL6 | NC1 | NC2 |
|---|---|---|---|---|---|---|---|---|
Sex | Male | Male | Female | Male | Male | Male | Male | Female |
Age (years old) | 65 | 54 | 68 | 60 | 58 | 45 | 66 | 49 |
Rai | IV | II | I | I | II | I | NA | NA |
Binet | C | B | A | A | B | A | NA | NA |
CLL-IPI risk | 4 | 4 | 2 | 1 | 3 | 4 | NA | NA |
MBC (×109/L) | 25.5 | 64.3 | 16.9 | 5.84 | 57 | 54.8 | NA | NA |
Platelets (× 109/L) | 99 | 261 | 170 | 167 | 154 | 167 | 223 | 173 |
Hemoglobin (g/L) | 123 | 158 | 119 | 146 | 129 | 146 | 158 | 142 |
CD4/CD8 (1–2.5) | 1.8 | 0.5 | 4.7 | NA | 1.3 | 0.71 | 1.49 | 1.18 |
β2-MG (μmol/L) | 2.85 | 1.9 | 2.37 | NA | 3.51 | 2.38 | NA | NA |
IGHV mutation | N | N | Y | Y | N | N | NA | NA |
17p- / TP53 mutation | Y | Y | N | N | N | Y | N | N |