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Fig. 3 | Molecular Cancer

Fig. 3

From: Methyltransferase like 7B is a potential therapeutic target for reversing EGFR-TKIs resistance in lung adenocarcinoma

Fig. 3

METTL7B promoted glutathione metabolism in LUAD cells. Untargeted metabolomic analysis by UPLC-MS/MS was detected in PC9 cells stably transfected with FLAG-NC or FLAG-METTL7B. a Heat map of differential metabolites. b KEGG pathway of differential metabolites. c and d ROC analysis for reduced glutathione and oxidized glutathione. e-i ROS level was detected in METTL7B-overexpressed PC9, HCC827 and METTL7B-suppressed PC9-GR, H1975 and PC9-OR cells. ***P < 0.001 and ****P < 0.0001

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Molecular Cancer

ISSN: 1476-4598