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Fig. 3 | Molecular Cancer

Fig. 3

From: CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells

Fig. 3

Category of the differential expression of genes and networks of the selected genes including the drug-resistant genes in KB-C2 and KB-C2-k.o.cdk6 cells. A Top10 KEGG pathways involved in the differential gene expression caused by knockout of cdk6 in KB-C2. B Network of enriched genes. The items are colored by cluster ID, where nodes that share the same cluster ID are typically close to each other. C Differential degree of the drug-resistant and -selected genes in KB-C2-k.o.cdk6 cells. D Protein-protein interaction network of the proteins that are most correlated with acquired drug resistance to endocrine therapy of cancers

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Molecular Cancer

ISSN: 1476-4598