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Fig. 7 | Molecular Cancer

Fig. 7

From: Circ-ZEB1 promotes PIK3CA expression by silencing miR-199a-3p and affects the proliferation and apoptosis of hepatocellular carcinoma

Fig. 7

Downregulation of circ-ZEB1 inhibits the formation of xenograft tumors in nude mice. A–C Xenograft formation, tumor volume, and tumor weight in nude mice, respectively. D, E Western blotting for PIK3CA in nude mice treated with HCC-LM3 cells transfected with Sh-circ-ZEB1 and NC. F, G IHC (*400) detects the positive rate of PIK3CA in nude mice treated with HCC-LM3 cells transfected with Sh-circ-ZEB1 and NC. *P < 0.05 versus the NC group. All data are presented as mean ± standard deviation (SD). The unpaired t-test was used to analyze the comparison between the two groups

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