Circ-ZEB1 promotes PIK3CA expression by silencing miR-199a-3p and affects the proliferation and apoptosis of hepatocellular carcinoma

Table 1 Clinicopathological characteristics of patients with HCC

Clinicopathologic characteristics	n	Overexpression n = 35	Non-overexpression n = 21	p-value
1) Age(years)				0.193
≤ 51	11	5	6
> 51	45	30	15
2) Sex				0.300
Male	29	20	9
Femle	27	15	12
3) Tumor size				*0.044*
≤ 5(cm)	13	7	6
> 5(cm)	43	28	15
4) TNM stage				*0.0002*
I-II	16	4	12
III-IV	40	31	9
5)Tumor multifocal				0.757
Absent	19	11	8
Present	37	24	13
6) Venous invasion				*0.011*
Absent	26	11	15
Present	30	24	8
7) HBsAg				0.053
Negative	28	14	14
Positive	28	21	7
8) AFP(ng/ml)				0.697
≤ 400	15	10	5
> 400	41	25	16
9) Cirrhosis				0.222
Absent	16	8	8
Present	40	27	13

ISSN: 1476-4598