Fig. 9From: PIK3CA mutations-mediated downregulation of circLHFPL2 inhibits colorectal cancer progression via upregulating PTENSchema of the positive feedback loop of sustained activation of PI3K/AKT via circLHFPL2/miR-556-5p and miR-1322/PTEN axis and downregulation of circLHFPL2 enhanced MEK inhibitor resistance by upregulating P-gp and BCRP in PIK3CA-mutant CRC cellsBack to article page