Skip to main content
Fig. 7 | Molecular Cancer

Fig. 7

From: Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis

Fig. 7

UbcH5c knockdown decreases the anticancer activity of DHPO. a and b The expression levels of indicated proteins in Panc1 and SW1990 cells transfected with shRNA targeting UbcH5c or control shRNA were determined by western blotting analysis after treatment with DHPO for 24 h. c and d The 72-h cell viability assays in indicated cell lines transfected with shRNA targeting UbcH5c or control shRNA. e Scheme showing a proposed molecular mechanism for the anticancer activity of DHPO

Back to article page