Fig. 3
From: Characterization of distinct circular RNA signatures in solid tumors
Characterization of differentially expressed circRNAs in seven solid tumors. A Total circRNA abundance in tested cancers. B Profiles of differentially expressed circRNAs identified in this study. The blue box indicates the unique circRNA expression signatures of each cancer. C The number of cancer-specific differentially expressed circRNAs. D List of differentially expressed circRNAs shared by at least two types of cancers. E Heatmap of twenty-five differentially expressed circRNAs shared by at least four types of cancers. The asterisk indicates circRNA expression is significantly altered. Red and green colors indicate upregulation and downregulation, respectively. F The number of differentially expressed circRNAs that exhibited consistent or inconsistent expression changes in at least two cancer types. G Expression alteration of RBPs associated with circRNA biogenesis in GBM. H eCLIP-seq read density for RBFOX1 within introns flanking hsa_circ_0111312 back-splicing site. The vertical red box indicates the GCATG binding motifs of RBFOX1