Skip to main content
Fig. 5 | Molecular Cancer

Fig. 5

From: The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway

Fig. 5

CircALG1 promoted migration and invasion through miR-342-5p in CRC. A Luciferase expression was normalized to Renilla luciferase expression, and the relative luciferase activity of miRNA mimic-transfected wells was compared with the control luciferase levels. B The luciferase activities were measured by a dual-luciferase assay, and the Renilla/firefly luciferase light-unit ratio was calculated. C qRT-PCR detection of miR-342-5p enrichment by circALG1 RAP assay. D-E Representative images and bar graphs of Transwell migration and invasion assays of cells with circALG1 overexpression and treatment with the miR-342-5p inhibitor (D) and cells with circALG1 inhibition and treatment with miR-342-5p mimics (E). The results are presented as the mean ± s.d. and are representative of at least 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, #p > 0.05

Back to article page

Molecular Cancer

ISSN: 1476-4598