Fig. 5
From: The functional roles of the circRNA/Wnt axis in cancer
The mechanisms of Wnt-associated circRNA in lung cancer. A In lung cancer, circ_0018414 inhibits cancer progression by regulating miR-6807-3p/DKK1 and the Wnt/β-catenin pathway. DKK1 is upregulated by circ_0018414, a ceRNA of miR-6783-3p. B Circ 0007059 inhibits the Wnt/β-catenin by acting as a sponge for miR-378. C Cir-ITCH upregulates ITCH expression to inactivate Wnt/β-catenin signaling by sponging miR-7 and miR-214