Clinicopathological parameters | No. of cases | CircHMGB2 expression level | P value | |
---|---|---|---|---|
Low | High | |||
Age | ||||
 ≥60 | 53 | 28 | 25 |  |
 <60 | 67 | 32 | 35 | 0.581 |
Gender | Â | Â | Â | Â |
 Male | 67 | 36 | 31 |  |
 Female | 53 | 24 | 29 | 0.358 |
Smoking history | ||||
 Smokers | 54 | 24 | 30 |  |
 Nonsmokers | 66 | 36 | 30 | 0.271 |
Histological type | ||||
 Adenocarcinoma | 78 | 41 | 37 |  |
 Squamous | 42 | 19 | 23 | 0.444 |
Tumor stage | ||||
 I–II | 72 | 31 | 41 |  |
 III–IV | 48 | 29 | 19 | 0.062 |
Lymph node metastasis | ||||
 Yes | 50 | 19 | 31 |  |
 NO | 70 | 41 | 29 | 0.026 |
Tumor size | ||||
 >2 cm | 55 | 21 | 34 |  |
 ≤2 cm | 65 | 39 | 26 | 0.017 |
Differentiation | ||||
 Well and moderate | 57 | 23 | 34 |  |
 Poor | 63 | 37 | 26 | 0.044 |