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Fig. 7 | Molecular Cancer

Fig. 7

From: Hsa-miR-3178/RhoB/PI3K/Akt, a novel signaling pathway regulates ABC transporters to reverse gemcitabine resistance in pancreatic cancer

Fig. 7

Hsa-miR-3178/RhoB axis mediated tumor growth and gemcitabine resistance by PI3K/Akt signaling pathway in PC cells. A-F Western blotting on the expression of RhoB, phosphorylated-PI3K, total PI3K, phosphorylated-Akt 308, phosphorylated-Akt 473, total Akt and P-gp, BCRP, MRP1 in the indicated cells. β-actin was used as a loading control. IC50: half-inhibitory concentration

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Molecular Cancer

ISSN: 1476-4598