Gene | Full name of gene | Functions | Ref |
---|---|---|---|
Shh, Ihh, Dhh | Hedgehog ligand | Positive regulator of the Hh pathway | [1] |
Ptch1 | Patched 1 | Negative regulator of the Hh pathway | [1] |
Smo | Smoothened | Positive regulator of the Hh pathway | [33] |
Sufu | Suppressed fusion protein | Negative regulator of the Hh pathway | [34] |
Gli1, Gli2, Gli3 | Glioma-associated oncogene 1, 2 and 3 | Positive or negative regulator of the Hh pathway | [24] |