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Fig. 9 | Molecular Cancer

Fig. 9

From: Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Fig. 9

Cell communication analysis in UCOGCP sample (pca_ai1). A, Major clusters of the UCOGCP sample shown in UMAP. B, Top three markers of each cluster obtained from “FindAllMarkers” function from Seurat package (4.0.4) shown in dot plot. C, The expression levels of epithelial marker genes and osteoclasts marker genes in different clusters. D, The number of potential ligand–receptor pairs analyzed by pyCellphoneDB (0.24). E, Ligand–receptor pairs shown in a bubble plot. F, The expression level of ligand–receptor pairs with high means. G, Survival analysis of gene signatures in F in pancreatic cancer using TCGA-PAAD on website Gepia2 (http://gepia2.cancer-pku.cn/#index). H, The expression level of ligand–receptor pairs among different samples

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Molecular Cancer

ISSN: 1476-4598