Skip to main content
Fig. 7 | Molecular Cancer

Fig. 7

From: Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer

Fig. 7

Receptor-ligand interaction analysis reveals the CXCR4/CXCL12 axis as a therapeutic target. A. CXCL12 expression in individual cell subtypes in the TME. The statistical significance of the CXCL12 expression difference between the Tumor—Benign Artery subtypes was tested using Wilcoxon's test. B Circos plot showing the results of a receptor-ligand interaction analysis using the CellPhoneDB algorithm. C Waterfall plot shows the top up-and downregulated pathways in tip cells compared to other endothelial cell phenotypes

Back to article page