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Fig. 2 | Molecular Cancer

Fig. 2

From: CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway

Fig. 2

CBX2 silencing alters leukemic cell survival and induces cell death. A and B Proliferation assay with shCBX2#1, shCBX2#2, and shSCR in U937 (A) and K562 (B) cells; experiments were performed at 7 days of puromycin selection; error bars show SD of three biological replicates (*P < 0.05, **P ≤ 0.01). C and D CCK8 assay of CBX2 knock-down and shSCR-transduced U937 (C) and K562 (D) cells; experiments were performed at 7 days of puromycin selection; error bars show SD of three biological replicates (*P < 0.05, **P ≤ 0.01). E and F Percentage of PI-positive shCBX2- and shSCR-transduced U937 (E) and K562 (F) cells; experiments were performed at 7 days of puromycin selection; error bars show SD of three biological replicates (*P < 0.05, **P ≤ 0.01)

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