Fig. 5

MTSS1 exerts tumor-suppressive effects in ovarian cancer cells. A qRT-PCR analysis of the expression of MTSS1 in A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls. B Western blot analysis of the expression of MTSS1, VIM, and Snail in A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls. C Growth curve of A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls as assessed using CCK-8 assays. D Proliferation of A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls as determined by colony formation assays. E Migration ability of A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls. F Invasion ability of A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative controls. G Growth curve of circFBXO7 overexpression A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative control siRNA. H Migration assays performed in circFBXO7 overexpression A2780 and MDAH2774 cells transfected with MTSS1 siRNA or negative control siRNA. *** P < 0.001, ** P < 0.01, * P < 0.05