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Fig. 1 | Molecular Cancer

Fig. 1

From: LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer

Fig. 1

LCT Activity Identified by Refuse in LUSC and LUAD. A Workflow of the Refuse analysis. B Bar plot shows total number of LCT events detected and a box plot showing expression of LCT (normalized as reads per million) for each patient. Red represents tumor samples and blue represents normal controls. C The proportion of LCT events in coding, UTR3 or UTR5 region, and proportion of LCT events in splicing or non-splicing region in TCGA LUSC and LUAD separately. D The absolute frequency of tumor and normal samples containing LCT affected genes. Each gene was calculated separately and top 20 most frequently represented genes were showed. E Enriched GO terms for genes recurrently affected by LCT (in more than 2 samples), dot size represents the number of genes enriched in each term and the color scale represents the -log10(p value) of enrichment

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